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質問 1：
A patient with diabetic ketoacidosis is receiving 0.9% NaCl, with potassium chloride 20 mEq/L, at 200 mL/h, and regular insulin 8 units/h, intravenously. After 8 hours, the blood glucose is
250 mg/dL and the anion gap is elevated. At this point, which of the following is the most appropriate therapy?
A. Convert to subcutaneous regular insulin and reduce fluids to a keep-vein-open rate.
B. Continue the current insulin and fluid therapy.
C. Continue the insulin infusion rate and change to dextrose-containing fluids.
D. Discontinue the insulin and maintain current fluids.
正解：B
質問 2：
A 65-year-old Woman presents with complaints of Worsening incontinence associated with sneezing and coughing, as well as itching in the genital area. Physical examination reveals some vaginal atrophy. A pad test is positive, post void residuals average 5 mL, and urinalysis is normal. Which of the following is the best treatment option for this patient?
A. Tamsulosin
B. Vaginal estrogen cream
C. Bethanechol
D. Tolterodine
正解：B
質問 3：
In designing a clinical trial, the method utilized to deal with inherent differences between groups is to:
A. Use blinding techniques.
B. Assign patients to groups randomly.
C. Use a control or comparison group.
D. Evaluate the results using statistical methods.
正解：A
質問 4：
A 53-year-old patient with an 8-year history of diabetes is currently taking glipizide 10 mg twice daily before breakfast and supper. The patient weighs 85 kg and reports a 4.5 kg weight gain in the last year. Laboratory results are:
Creatinine: 1.2 mg/dL
A1C: 8.5%
What is the most appropriate recommendation at this time for improved diabetes control?
A. Increase glipizide to 20 mg twice daily.
B. Change glipizide to insulin.
C. Change glipizide to metformin.
D. Continue with glipizide and add metformin.
正解：C
質問 5：
Which statement regarding vaccine administration in infants and children is correct?
A. There is no limit to the number of vaccines an individual may receive at one visit.
B. Live Vaccines should be administered at least 2 Weeks before killed Vaccines in infants less than 6 months old.
C. The appropriate administration site is the deltoid.
D. The vaccines may be combined in the same syringe.
正解：C
質問 6：
A 72-year-old woman with a long history of schizophrenia has been admitted to the state hospital because of a recent relapse while on risperidone 5 mg daily. It is decided to use an equivalent dose of ziprasidone. Which reference would most likely provide this information?
A. Diagnostic and Statistical Manual of Mental Disorders - V
B. Martindale: The Complete Drug Reference
C. Drug Facts & Comparisons
D. The Sanford Guide
正解：B
質問 7：
From ethical and scientific validity standpoints, in addition to double blinding, which of the following research designs is best for determining a new medication's relative efficacy in treating acute stroke?
A. Crossover design comparing the new therapy with the best standard therapy
B. Placebo-controlled, crossover design
C. Parallel design comparing the new therapy with the best standard therapy
D. Placebo-controlled, randomized, parallel design
正解：A
A patient with diabetic ketoacidosis is receiving 0.9% NaCl, with potassium chloride 20 mEq/L, at 200 mL/h, and regular insulin 8 units/h, intravenously. After 8 hours, the blood glucose is
250 mg/dL and the anion gap is elevated. At this point, which of the following is the most appropriate therapy?
A. Convert to subcutaneous regular insulin and reduce fluids to a keep-vein-open rate.
B. Continue the current insulin and fluid therapy.
C. Continue the insulin infusion rate and change to dextrose-containing fluids.
D. Discontinue the insulin and maintain current fluids.
正解：B
質問 2：
A 65-year-old Woman presents with complaints of Worsening incontinence associated with sneezing and coughing, as well as itching in the genital area. Physical examination reveals some vaginal atrophy. A pad test is positive, post void residuals average 5 mL, and urinalysis is normal. Which of the following is the best treatment option for this patient?
A. Tamsulosin
B. Vaginal estrogen cream
C. Bethanechol
D. Tolterodine
正解：B
質問 3：
In designing a clinical trial, the method utilized to deal with inherent differences between groups is to:
A. Use blinding techniques.
B. Assign patients to groups randomly.
C. Use a control or comparison group.
D. Evaluate the results using statistical methods.
正解：A
質問 4：
A 53-year-old patient with an 8-year history of diabetes is currently taking glipizide 10 mg twice daily before breakfast and supper. The patient weighs 85 kg and reports a 4.5 kg weight gain in the last year. Laboratory results are:
Creatinine: 1.2 mg/dL
A1C: 8.5%
What is the most appropriate recommendation at this time for improved diabetes control?
A. Increase glipizide to 20 mg twice daily.
B. Change glipizide to insulin.
C. Change glipizide to metformin.
D. Continue with glipizide and add metformin.
正解：C
質問 5：
Which statement regarding vaccine administration in infants and children is correct?
A. There is no limit to the number of vaccines an individual may receive at one visit.
B. Live Vaccines should be administered at least 2 Weeks before killed Vaccines in infants less than 6 months old.
C. The appropriate administration site is the deltoid.
D. The vaccines may be combined in the same syringe.
正解：C
質問 6：
A 72-year-old woman with a long history of schizophrenia has been admitted to the state hospital because of a recent relapse while on risperidone 5 mg daily. It is decided to use an equivalent dose of ziprasidone. Which reference would most likely provide this information?
A. Diagnostic and Statistical Manual of Mental Disorders - V
B. Martindale: The Complete Drug Reference
C. Drug Facts & Comparisons
D. The Sanford Guide
正解：B
質問 7：
From ethical and scientific validity standpoints, in addition to double blinding, which of the following research designs is best for determining a new medication's relative efficacy in treating acute stroke?
A. Crossover design comparing the new therapy with the best standard therapy
B. Placebo-controlled, crossover design
C. Parallel design comparing the new therapy with the best standard therapy
D. Placebo-controlled, randomized, parallel design
正解：A
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