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質問 1：
RL is a 54 YOM who's calculated 10-year atherosclerotic cardiovascular disease (ASCVD) risk is 18 %.
Which of the following is the most appropriate pharmacotherapy recommendation for CR?
A. Pravastatin 20 mg PO QHS
B. Rosuvastatin 10 mg PO QHS
C. Lovastatin 10 mg PO QHS
D. Atorvastatin 80 mg PO QHS
E. Atorvastatin 20mg PO QHS
正解：D
解説: (Pass4Test メンバーにのみ表示されます)
質問 2：
LN is 84 YOM who is in hospital for a back surgery. His height is 5 feet and 4 inches, weight 85 kg and NKDA.
His past medical history includes hypertension, diabetes mellitus, major depression, hypothyroidism and chronic back pain. Post-op day 1, LN's medication includes Dexamethasone 8mg iv q6h with taper dosing, Ondansetron 4mg iv q6h prn for N/V, Levothyroxine 0.075mg po daily, Lisinopril 10mg po daily, Citalopram
20mg po daily, Docusate sodium / Senna 1 tab po twice a day, Bisacodyl 10mg suppository daily prn for constipation, Famotidine 20 mg iv q12hr, Metoclopramide 10mg iv q6h, Metformin 500mg po bid, D51/2NS with 20K at 125 mls/hour and Hydromorphone PCA at 0.2 mg/hour of basal rate, demand dose 0.1mg.
lock-out every 6min, one hour limit 2.2mg/hour. Pertinent morning labs includes serum creatinine 1.4mg/dl, Mg 1.5mg/ dl, K 5.0mmol/L, Na 135mmol/L. Day 3 post-operation LN's pain was much better and only used
3 mg of hydromorphone in the 24hrs.
Physician wants to change to oral morphine. What would be your best recommendation?
A. Morphine 30mg ER po q6hr and morphine 5mg q6h prn for breakthrough pain
B. Morphine 60mg ER po daily and morphine 15mg po q6h prn breakthrough pain
C. Morphine SR 10mg po daily and morphine 5mg po q6h prn for breakthrough pain
D. Morphine 15mg ER po q12hr and morphine 5mg po q6h prn breakthrough pain
E. Morphine 15mg ER po q12hr and morphine 15mg po q6h prn for breakthrough pain
正解：D
解説: (Pass4Test メンバーにのみ表示されます)
質問 3：
According to the 2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults, which of the following medications and dosing regimens is considered moderate-intensity statin therapy?
A. Simvastatin 40 mg PO QHS
B. Lovastatin 20 mg PO QHS
C. Atorvastatin 80 mg PO QHS
D. Atorvastatin 20mg PO QHS
E. Rosuvastatin 40 mg PO QHS
正解：D
解説: (Pass4Test メンバーにのみ表示されます)
質問 4：
LN is 84 YOM who is in hospital for a back surgery. His height is 5 feet and 4 inches, weight 85 kg and NKDA.
His past medical history includes hypertension, diabetes mellitus, major depression, hypothyroidism and chronic back pain. Post-op day 1, LN's medication includes Dexamethasone 8mg iv q6h with taper dosing, Ondansetron 4mg iv q6h prn for N/V, Levothyroxine 0.075mg po daily, Lisinopril 10mg po daily, Citalopram
20mg po daily, Docusate sodium / Senna 1 tab po twice a day, Bisacodyl 10mg suppository daily prn for constipation, Famotidine 20mg iv q12hr, Metoclopramide 10mg iv q6h, Metformin 500mg po bid, D51/2NS with 20K at 125mls/hour and Hydromorphone PCA at 0.2mg/hour of basal rate, demand dose 0.1mg. lock-out every 6min, one hour limit 2.2mg/hour. Pertinent morning labs includes serum creatinine 1.4mg/dl, Mg 1.5mg/ dl, K 5.0mmol/L, Na 135mmol/L.
Which of the following medication's dose are adjusted for poor renal function?
A. Lisinopril
B. Metoclopramide
C. Ondansetron
D. Famotidine
E. Citalopram
正解：B
解説: (Pass4Test メンバーにのみ表示されます)
質問 5：
An order is received for heparin 18 units per kg per hour on a patient whose weight is 125lb. The IV bag comes as a concentration of 50 units /mL. Calculate the infusion rate in terms of mL/hr.
A. 40.9 mls/hr
B. 20.45 mls/hr
C. 18 mls/hr
D. 10.23 mls/hr
E. 5.15 mls/hr
正解：B
解説: (Pass4Test メンバーにのみ表示されます)
質問 6：
Which of the following is/are nominal data?
A. Sex
B. Stages of breast cancer
C. Blood Group
D. NYHA stages I-IV
E. Race
正解：C
解説: (Pass4Test メンバーにのみ表示されます)
質問 7：
Select the class of Anti-diabetic medication that works in the specified organ to prevent hyperglycemia. Select all that applies. Brain (E)
A. Biguanide
B. Glucagon-like peptide-1 receptor agonists
C. Alpha- Glucosidase Inhibitors
D. DPP4 Inhibitors
E. Thiazolidinediones
F. Sulfonylureas
G. SGLT2 inhibitors
正解：B
解説: (Pass4Test メンバーにのみ表示されます)
質問 8：
A 55-year-old female is receiving chemotherapy for metastatic carcinoma. She threatens to stop her treatment because of severe nausea and vomiting. The oncologist plans to use prochlorperazine to reduce the nausea and vomiting associated with chemotherapeutic agents. What is the mechanism of action of prochlorperazine?
A. H2 receptor antagonist
B. Cannabinoids related
C. Blocking dopamine receptors
D. Blockage of prostaglandins
E. Serotonin 5-HT3 antagonist
正解：C
解説: (Pass4Test メンバーにのみ表示されます)
質問 9：
A physician needs your help to calculate the protamine dose on a patient who started hemorrhaging while on heparin. Patient has been receiving heparin at a dose of 13mls/hr for 2 hrs when the physician decides to use protamine to reverse the heparin. Heparin bag says concentration of 50 units/ml. The half-life of heparin is 60 minutes. 1 mg of protamine reverses 100 units of heparin.
How much protamine should be given to this patient?
A. 9.7mg
B. 13mg
C. 5mg
D. 10mg
E. 7mg
正解：A
解説: (Pass4Test メンバーにのみ表示されます)
RL is a 54 YOM who's calculated 10-year atherosclerotic cardiovascular disease (ASCVD) risk is 18 %.
Which of the following is the most appropriate pharmacotherapy recommendation for CR?
A. Pravastatin 20 mg PO QHS
B. Rosuvastatin 10 mg PO QHS
C. Lovastatin 10 mg PO QHS
D. Atorvastatin 80 mg PO QHS
E. Atorvastatin 20mg PO QHS
正解：D
解説: (Pass4Test メンバーにのみ表示されます)
質問 2：
LN is 84 YOM who is in hospital for a back surgery. His height is 5 feet and 4 inches, weight 85 kg and NKDA.
His past medical history includes hypertension, diabetes mellitus, major depression, hypothyroidism and chronic back pain. Post-op day 1, LN's medication includes Dexamethasone 8mg iv q6h with taper dosing, Ondansetron 4mg iv q6h prn for N/V, Levothyroxine 0.075mg po daily, Lisinopril 10mg po daily, Citalopram
20mg po daily, Docusate sodium / Senna 1 tab po twice a day, Bisacodyl 10mg suppository daily prn for constipation, Famotidine 20 mg iv q12hr, Metoclopramide 10mg iv q6h, Metformin 500mg po bid, D51/2NS with 20K at 125 mls/hour and Hydromorphone PCA at 0.2 mg/hour of basal rate, demand dose 0.1mg.
lock-out every 6min, one hour limit 2.2mg/hour. Pertinent morning labs includes serum creatinine 1.4mg/dl, Mg 1.5mg/ dl, K 5.0mmol/L, Na 135mmol/L. Day 3 post-operation LN's pain was much better and only used
3 mg of hydromorphone in the 24hrs.
Physician wants to change to oral morphine. What would be your best recommendation?
A. Morphine 30mg ER po q6hr and morphine 5mg q6h prn for breakthrough pain
B. Morphine 60mg ER po daily and morphine 15mg po q6h prn breakthrough pain
C. Morphine SR 10mg po daily and morphine 5mg po q6h prn for breakthrough pain
D. Morphine 15mg ER po q12hr and morphine 5mg po q6h prn breakthrough pain
E. Morphine 15mg ER po q12hr and morphine 15mg po q6h prn for breakthrough pain
正解：D
解説: (Pass4Test メンバーにのみ表示されます)
質問 3：
According to the 2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults, which of the following medications and dosing regimens is considered moderate-intensity statin therapy?
A. Simvastatin 40 mg PO QHS
B. Lovastatin 20 mg PO QHS
C. Atorvastatin 80 mg PO QHS
D. Atorvastatin 20mg PO QHS
E. Rosuvastatin 40 mg PO QHS
正解：D
解説: (Pass4Test メンバーにのみ表示されます)
質問 4：
LN is 84 YOM who is in hospital for a back surgery. His height is 5 feet and 4 inches, weight 85 kg and NKDA.
His past medical history includes hypertension, diabetes mellitus, major depression, hypothyroidism and chronic back pain. Post-op day 1, LN's medication includes Dexamethasone 8mg iv q6h with taper dosing, Ondansetron 4mg iv q6h prn for N/V, Levothyroxine 0.075mg po daily, Lisinopril 10mg po daily, Citalopram
20mg po daily, Docusate sodium / Senna 1 tab po twice a day, Bisacodyl 10mg suppository daily prn for constipation, Famotidine 20mg iv q12hr, Metoclopramide 10mg iv q6h, Metformin 500mg po bid, D51/2NS with 20K at 125mls/hour and Hydromorphone PCA at 0.2mg/hour of basal rate, demand dose 0.1mg. lock-out every 6min, one hour limit 2.2mg/hour. Pertinent morning labs includes serum creatinine 1.4mg/dl, Mg 1.5mg/ dl, K 5.0mmol/L, Na 135mmol/L.
Which of the following medication's dose are adjusted for poor renal function?
A. Lisinopril
B. Metoclopramide
C. Ondansetron
D. Famotidine
E. Citalopram
正解：B
解説: (Pass4Test メンバーにのみ表示されます)
質問 5：
An order is received for heparin 18 units per kg per hour on a patient whose weight is 125lb. The IV bag comes as a concentration of 50 units /mL. Calculate the infusion rate in terms of mL/hr.
A. 40.9 mls/hr
B. 20.45 mls/hr
C. 18 mls/hr
D. 10.23 mls/hr
E. 5.15 mls/hr
正解：B
解説: (Pass4Test メンバーにのみ表示されます)
質問 6：
Which of the following is/are nominal data?
A. Sex
B. Stages of breast cancer
C. Blood Group
D. NYHA stages I-IV
E. Race
正解：C
解説: (Pass4Test メンバーにのみ表示されます)
質問 7：
Select the class of Anti-diabetic medication that works in the specified organ to prevent hyperglycemia. Select all that applies. Brain (E)
A. Biguanide
B. Glucagon-like peptide-1 receptor agonists
C. Alpha- Glucosidase Inhibitors
D. DPP4 Inhibitors
E. Thiazolidinediones
F. Sulfonylureas
G. SGLT2 inhibitors
正解：B
解説: (Pass4Test メンバーにのみ表示されます)
質問 8：
A 55-year-old female is receiving chemotherapy for metastatic carcinoma. She threatens to stop her treatment because of severe nausea and vomiting. The oncologist plans to use prochlorperazine to reduce the nausea and vomiting associated with chemotherapeutic agents. What is the mechanism of action of prochlorperazine?
A. H2 receptor antagonist
B. Cannabinoids related
C. Blocking dopamine receptors
D. Blockage of prostaglandins
E. Serotonin 5-HT3 antagonist
正解：C
解説: (Pass4Test メンバーにのみ表示されます)
質問 9：
A physician needs your help to calculate the protamine dose on a patient who started hemorrhaging while on heparin. Patient has been receiving heparin at a dose of 13mls/hr for 2 hrs when the physician decides to use protamine to reverse the heparin. Heparin bag says concentration of 50 units/ml. The half-life of heparin is 60 minutes. 1 mg of protamine reverses 100 units of heparin.
How much protamine should be given to this patient?
A. 9.7mg
B. 13mg
C. 5mg
D. 10mg
E. 7mg
正解：A
解説: (Pass4Test メンバーにのみ表示されます)
Yuyama -
先日申込みましたNAPLEXを本日受験し、無事に合格することができました。
ほとんど出題されました。ありがとうございました。